110: 3D-LUXE: A modular 3D-printed platform for high-throughput photochemical experimentation

Abstract: A modular, 3D printed system for miniaturized, high throughput photochemical experimentation has been developed to advance sustainable reaction optimization. The platform supports parallel photoredox screening in 16- or 96-well configurations, enabling rapid generation of large datasets while significantly reducing material consumption, energy usage, and overall environmental impact. Initial characterization data for both system configurations, validation results from pharmaceutically relevant cross-coupling reactions, and design considerations of the 3D printed device are discussed to support rapid and straightforward adoption. This approach offers a cost-effective and environmentally responsible tool that can be readily adopted across diverse research environments.